06/19/2022
Scientific Study Finds That Kratom Has Insulin-Like Action, And Therefore Kratom Has Anti-Diabetic Properties
~ from Kratom Herald
(link to full story below)
"The scientists who conducted this study did experiments with muscle cells and various forms of Kratom, in order to confirm if Kratom really has anti-diabetic effects, and if so, the underlying mechanisms responsible for these effects.
It was found that full spectrum Kratom extract and isolated Mitragynine stimulated the uptake of glucose, which is a critical property of anti-diabetic medications like insulin. Indeed, once again, the whole point of insulin is to increase the uptake of sugar (glucose) in order to bring sugar levels in the body back to normal.
The scientists even say that Kratom has a similar effect to insulin. Further, it was found that combining Kratom with insulin leads to even more powerful glucose uptake than insulin alone.
The scientists dived deeper into why this is the case, and found that Kratom reduces glucose via similar mechanisms to insulin. Although the science is complex, it comes down to Kratom interacts with key enzymes which stimulate glucose uptake. One specific example is that Kratom interacts with GLUT1 in a way which increases the amount of cell surface transporters and therefore increases glucose uptake. Also, Kratom changes the distribution of GLUT4 across the plasma membrane, also increasing glucose uptake.
Another important note is that the scientists found full spectrum Kratom has more anti-diabetic effects than Mitragynine alone, indicating that multiple alkaloids are involved with Kratomβs anti-diabetic effects, and therefore natural/full spectrum Kratom is the most effective."
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