Walmart Tupelo - W Main St

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Walmart Tupelo - W Main St Sam was a firm believer in listening to what his customers had to say. That tradition continues today. But now, it doesn’t have to end when you leave the store.

Pharmacy Phone: 662-842-9375

Pharmacy Hours:
Monday: 9:00 AM - 7:00 PM
Tuesday: 9:00 AM - 7:00 PM
Wednesday: 9:00 AM - 7:00 PM
Thursday: 9:00 AM - 7:00 PM
Friday: 9:00 AM - 7:00 PM
Saturday: 9:00 AM - 7:00 PM
Sunday: 10:00 AM - 6:00 PM


Services at this Location:
• Grocery Pickup
• Pharmacy
• Auto Care Center
• Vision Center
• Wireless Services
• Pickup
• Garden Center
• Photo Center
• Bakery
• Deli
• Grocery
• liquor


When Sam Walton opened the doors to the first Walmart in 1962, his goal was to save people money so they can live better. Through Facebook, we’re able to talk to you, find out what’s on your mind and let you know what we’re up to. It’s just another way we’re working to give the millions of families who shop at Walmart more of what they love—ways to save money and live better.

Join us today from 10am – 2pm for The Wellness Event💙💉! Don’t miss no-cost immunizations like flu & COVID-19 to help pro...
10/17/2026

Join us today from 10am – 2pm for The Wellness Event💙💉! Don’t miss no-cost immunizations like flu & COVID-19 to help protect your family this season, free health screenings, giveaways and the chance to talk with your pharmacist*. Take time for your health this fall with help from Walmart.

Learn more at https://www.walmart.com/wellnesshub

*Immunizations are $0 copay with most insurances. Restrictions apply. Giveaways available while supplies last.

Walmart shoppers, take time for your health this fall! 🍂💉 The Wellness Event is coming up in-store on Saturday, October ...
10/15/2026

Walmart shoppers, take time for your health this fall! 🍂💉 The Wellness Event is coming up in-store on Saturday, October 17, from 10 a.m.–2 p.m.

Join us for no-cost immunizations like flu & COVID-19 to help protect your family this season, free health screenings, giveaways & the chance to talk with your pharmacist*.

Visit https://www.walmart.com/wellnesshub to learn more.

*Immunizations are $0 copay with most insurances. Restrictions apply. Subject to availability. Giveaways while supplies last.

10/10/2026

Join iconic comic creator Stan Sakai for a closer look at collectible action figures, live from NYCC. Comment SHOP to receive a link to purchase these products!

Keep your eyes protected while you watch the game! At the Walmart Vision center, we have popular brands like Costa, Ray...
10/09/2026

Keep your eyes protected while you watch the game! At the Walmart Vision center, we have popular brands like Costa, Ray-Ban, Oakley, and more! Come find your favorite pair today!

10/09/2026

Join Todd McFarlane for a closer look at collectible action figures, live from NYCC. Comment SHOP to receive link to order these McFarlane products!

10/08/2026

Join GaryVee for a closer look at graded comics, live from New York Comic Con. Comment SHOP to receive a link to order VeeFriends products!

10/08/2026

don’t overthink it 🦋

shop deals Oct 5-11

Your eyes deserve the best protection! Whether you're working, creating, or tackling projects, protect your eyes with qu...
10/07/2026

Your eyes deserve the best protection! Whether you're working, creating, or tackling projects, protect your eyes with quality safety eyewear! Stop by Walmart Vision Center, where you will find style, comfort, and protection for your eyes!

10/06/2026

Ready, set—shop! 🏁 Kick off the Walmart Deals event with Ally Love for fun games, great finds & prices that can’t be beat.Tune in October 5at 10pm ET.

10/04/2026

they’re tiny. our deals are not. shop Oct 5-11 🔥

10/03/2026

Why choose between Mellon Collie and Siamese Dream when you can have the best of both?

Enjoy all The Smashing Pumpkins greatest hits with the Walmart Exclusive Absolute Zeros vinyl: https://walmrt.us/4AO4r6w

10/02/2026

coming to a karaoke room near you - ‘Catchin’ Feels’ by Alwayz 🦋

shop deals Oct 5-11

Get a new look for fall like this Lacoste frame for $150! Can't decide on one frame...get more than one and save 20% off...
10/02/2026

Get a new look for fall like this Lacoste frame for $150! Can't decide on one frame...get more than one and save 20% off each additional pair!

October is Contact Lens Safety Month...come see the savings! We can get you a year's supply for low cost, making it conv...
09/30/2026

October is Contact Lens Safety Month...come see the savings! We can get you a year's supply for low cost, making it convenient to be compliant!

Yeah, our bakers are this good 👀
09/25/2026

Yeah, our bakers are this good 👀

Tomorrow is Family Health & Fitness Day! Come see our assortment of Sport and Safety Frames to protect your eyes during ...
09/25/2026

Tomorrow is Family Health & Fitness Day! Come see our assortment of Sport and Safety Frames to protect your eyes during all of the activities that keep you healthy and fit!

Home is where the haunt is 👻
09/23/2026

Home is where the haunt is 👻

Keep your glasses and devices clean on the go! Get a box of Zeiss wipes 100 count for $5.72!
09/23/2026

Keep your glasses and devices clean on the go! Get a box of Zeiss wipes 100 count for $5.72!

Guys- get a new look for fall! Like these Reverb frames for $130. Save 20% with each additional pair, 35% when you purch...
09/18/2026

Guys- get a new look for fall! Like these Reverb frames for $130. Save 20% with each additional pair, 35% when you purchase sunglasses!

Flu protection starts here! 😷 Get your no-cost flu shot* right here at your Walmart Pharmacy during our Immunization Eve...
09/18/2026

Flu protection starts here! 😷 Get your no-cost flu shot* right here at your Walmart Pharmacy during our Immunization Event on September 23 from 10am-2pm.

Can't make it then? Schedule an appointment in-app or stop by the Pharmacy.
👉 Schedule now: walmart.onelink/Ulev/FluShots

*$0 copay with most insurances. Restrictions apply.

Address

2270 W Main Street
Tupelo, MS
38801

Opening Hours

Monday 6am - 11pm
Tuesday 6am - 11pm
Wednesday 6am - 11pm
Thursday 6am - 11pm
Friday 6am - 11pm
Saturday 6am - 11pm
Sunday 6am - 11pm

Telephone

+16628444011

Website

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